Principle of 3-part Hematology Analyzer-seamaty Medical Equipment Supplier

release time:2022-09-22 11:41:04

Hematology analyzers are one of the most widely used instruments for clinical testing in hospitals. Hematology analyzers are computerized, highly specialized machines that calculate the number of different types of red color and the levels of white blood cells, platelets, hemoglobin and hematocrit in a blood sample. Hematology analyzers are involved in the detection, monitoring, prognosis and follow-up screening of diseases and are widely used for a variety of blood-related disorders, such as hemophilia, blood cancers and blood clots. Other disorders include leukemia, anemia, blood transfusions, malignant lymphoma and other diseases diagnosed using hematology.

Many hospitals and clinics currently use 3-part and 5-part Differential Hematology Analyzers more often. The following is an introduction to the 3-part Differential Hematology Analyzers.

3-part Differential Hematology Analyzer

1. 3-Part Differential Hematology Analyzers Principle: Resistive Resistance Hematology

The 3-part Differential Hematology Analyzers use the instantaneous change in electrical resistance of blood cells passing through the micropores to generate a pulse current for counting. Dilute specimens of white and red blood cells are passed through their respective counting microwells and into their respective channels under the control of a negative pressure. The cell signals are then screened, amplified and counted by two photoelectric sensors.

a. Microtubes: A standard size ruby hole is set at its lower end. rbc tube hole; 80 microns; wbc tube hole diameter: 100 microns. Easy to clog, prevent plugging and maintenance.

b. Micron Counting: impurities other than cells will be mistaken for cell counting. Ensure the quality of the diluent and the cleanliness of the environment.

c. Cells can overlap each other through the micropores and produce bias: blood samples should be adequately diluted (WBC1:256, RBC1:5056) and designed with techniques to correct for bias.

2. Histogram of 3-part Differential Hematology Analyzers

The histogram is obtained by measuring the accumulation of each cell pulse through the sensing area. 3-part Differential Hematology Analyzers' histogram is the information reflecting cell size heterogeneity.

The computer divides the leukocyte volume from 30 to 450 fl into 256 channels. Each lane is 1.64 microliters, and the leukocytes in the sample are placed in separate lanes according to their size. This resulted in a histogram plotted by size and number. The peak points of each channel were connected with a curve to produce a report.

Three types of cell histograms are available and can be further analyzed by the instrument's memory program: mean red blood cell volume, red blood cell distribution width, mean platelet volume, and white blood cell trichome results.

3. 3-part Differential Hematology Analyzers for cell trichotomies

Mature leukocytes include neutrophils, lymphocytes and eosinophils, basophils, and monocytes. Among them, neutrophils are the most abundant. This is followed by lymphocytes. The other three cell types do not add up to more than 10%.

The various cells in the diluent, by the action of hemolytic agents, dissolve the membrane of the leukocytes. Only the nucleus and granules are left behind and the cells are reduced in size. The original largest monocytes fall between lymph and neutrophils in size after lysis and action. This divides the leukocytes into three parts according to their size.

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