Microfluidic Marvel: The Seamaty SD1 Dry Chemistry Analyzer's Test Tray Workflow

release time:2024-07-09 15:08:03

This blog post dives into the fascinating world of the Seamaty SD1 dry chemistry analyzer, specifically exploring the inner workings of its test tray workflow.

Faster, Easier, More Accurate Diagnosis:

The Seamaty SD1 revolutionizes medical testing by providing on-site results using a mere 0.1cc of whole blood, serum, or plasma. This fully automated analyzer boasts built-in centrifugation, QR code compatibility, and real-time quality control, leading to faster, easier, and more accurate diagnoses within just 12 minutes.

Replacing the Bulky with the Brilliant:

Gone are the days of cumbersome biochemical machines. The Seamaty SD1 utilizes pre-packaged, lyophilized reagent kits that require no manual diluent addition. These refrigerated kits (2-8°C) offer a remarkable one-year shelf life. But how does this compact system achieve the accuracy of its larger counterparts?

A Closer Look: The Test Tray's Dance

The magic unfolds within the test tray. Here's a step-by-step breakdown:

Step 1: Loading and Initial Mixing (0 seconds)

Roughly 100uL of sample is added to the designated well on the test disc.
The disc is then placed in the instrument's telescoping bin, which seamlessly transports it to its working position.
A top bar secures the tray while the integrated dilution cup rises, puncturing itself to release diluent and top itself off.

Step 2: Centrifugal Separation (0-140 seconds)

High-speed rotation by the instrument's motor propels the sample and diluent outward within the test disc (centrifugation).
This centrifugal force separates the sample into plasma at the center and blood cells at the periphery.
Simultaneously, a specific volume of diluent fills a dedicated chamber for color assays and another collects excess diluent.

step 2.jpg

Step 3: Precise Mixing (140-210 seconds)

A combination of siphoning force and centrifugal force carefully guides the sample and pre-measured diluent into the mixing chamber.
The instrument employs alternating acceleration and deceleration maneuvers to ensure homogenous mixing.

step 3.jpg

Step 4: Sample Distribution and Reaction (210-432 seconds)

The diluted sample is strategically distributed into designated colorimetric chambers containing various biochemical reagents.

Step 5: Colorimetric Detection and Analysis (432-672 seconds)

Chemical reactions within each chamber commence, generating colors indicative of specific biochemical concentrations.
The SD1 utilizes constant light source detection technology, employing a halogen lamp to ensure a stable light source with minimal intensity variations (less than 1%). This surpasses traditional xenon lamp performance.

The Power of Microfluidics and Spectrophotometry:

By seamlessly integrating microfluidics with spectrophotometry, the SD1's built-in centrifuge further enhances accuracy, adhering to Lambert's Law.

Related further reading

1. Say Goodbye to Manual Labor: Experience the Automated Ease of Seamaty SD1 Chemistry Analyzer

2. Seamaty SD1 vs. Mindray BS-480 Chemistry Analyzer: Which One is Better for Your Needs?

3. How Seamaty SD1 Revolutionize Small Clinic Diagnostics: Advantages and Case Studies

4. Selecting the Perfect Chemistry Analyzer for Small Labs: Seamaty SD1 vs. Beckman Coulter DxC 700 AU

5. Top 9 Clinical Chemistry Analyzers for Small to Mid-Sized Laboratories in 2024

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