release time:2024-05-24 14:50:07
Blood gas analysis is a critical diagnostic tool used to evaluate respiratory function, acid-base balance, and metabolic status in real-time, reflecting the patient's current condition. It aids in clinical monitoring and treatment adjustment across various medical fields.
But what exactly is blood gas analysis and how does a blood gas analyzer work? What are its clinical implications, common parameters, and application scenarios? Let’s explore these aspects together.
Blood gas analysis involves a comprehensive examination of various gases and acidic or basic substances in the blood, with common indicators including partial pressure of oxygen (pO2), partial pressure of carbon dioxide (pCO2), and pH levels. Broadly, it also includes analysis of electrolytes, lactate, glucose, and their derivatives.
This analysis is vital for managing respiratory failure due to pulmonary diseases, critical care, internal medicine, surgery, obstetrics, pediatrics, shock, major burns, and surgical procedures. It is now widely used in clinical departments of hospitals.
The primary clinical significance of blood gas analysis is to assess respiratory function and acid-base balance in the body. It helps:
Parameter |
Description |
Reference Range |
pH |
Indicates blood acidity or alkalinity. Arterial pH < 7.35 indicates acidosis, and > 7.45 indicates alkalosis. Normal pH does not always mean there is no acid-base imbalance; other indicators should be considered. |
7.35-7.45 |
pCO2 |
Reflects alveolar ventilation efficiency. |
35-45 mmHg |
pO2 |
Indicates oxygen partial pressure in the blood. |
83-108 mmHg / 11.1-14.4 kPa |
Na+ |
Essential for extracellular fluid volume, osmotic pressure, acid-base balance, and cellular function. |
138-146 mmol/l |
K+ |
Main cation for cellular activity; important for maintaining normal osmotic pressure, acid-base balance, glucose and protein metabolism, and neuromuscular function. High levels can cause arrhythmias. |
3.5-4.9 mmol/l |
Ca2+ |
Vital for neuromuscular excitability, gland secretion, and enzyme activity. |
1.12-1.32 mmol/l |
Cl- |
Major extracellular anion; useful in differentiating types of metabolic acidosis. |
98-109 mmol/l |
Glu (Glucose) |
Essential nutrient for metabolism. |
3.9-5.8 mmol/l |
Lac (Lactate) |
Elevated levels indicate reduced blood perfusion or tissue hypoxia. |
0.36-1.25 mmol/l |
Hct (Hematocrit) |
Percentage of red blood cells in blood; impacts blood viscosity and reflects red cell mass. |
38-51% |
HCO3- (Bicarbonate) |
Indicates actual bicarbonate content in the blood; crucial for acid-base balance. |
21-28 mmol/l |
Emergency Resuscitation: In emergency settings, patients often experience metabolic imbalances. Rapid acquisition of blood pH, pO2, and pCO2 values is essential for correcting acid-base imbalances and effectively resuscitating patients.
Blood gas analysis is indispensable in clinical practice, offering critical insights for diagnosis, treatment, and prognosis. Its reports provide robust evidence for clinical decisions and help prevent medical disputes through evidence-based practice.
- Portable and efficient: Handheld operation with results in three steps.
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1)Add a sample volume of 100 μl to the reagent tray, with a permissible sample range of 90-120 μl (it is recommended that a blood volume of at least 250 μl be collected for review).2) The use of lithium heparin anticoagulation tubes is recommended for sample processing.