Dry chemistry analytical techniques are relative to wet chemistry techniques. Dry chemistry is the direct addition of a liquid test sample to a dry reagent produced specifically for a different project. The moisture of the sample under test is used as a solvent to cause a specific chemical reaction, which leads to a chemical analysis method. Dry chemistry is a class of analytical methods based on enzymatic methods. Dry chemistry can also be called solid phase chemistry. Dry chemistry uses reflectance photometry or differential electrode method as a measurement method.
Advantages of dry chemistry
-
1) High accuracy and speed, test results can be made within 3~4 min;
-
2) Easy to operate, no need for daily calibration;
-
3) No need to store any other reagents or prepare any solution;
-
4) Specimen does not need to be pre-treated, the multilayer membrane has the function of selective filtration, thus reducing the influence of interfering substances in the process of determination;
-
5) The amount of specimen is small, and the water in the reaction is supplied by the liquid component of the specimen, which improves the sensitivity of the determination;
-
6) The multilayer membrane based on the principle of differential electrode method is disposable, so it has the advantages of conventional electrode method without its disadvantages;
-
7) In some cases, it can replace the wet chemical method for emergency specimens. It can also be used for the methodological evaluation of routine test results, etc.
Dry chemistry can be used not only for qualitative examination. It has also been developed as a semi-quantitative and quantitative analytical method. Dry chemistry has become an important class of methods in clinical testing. Dry chemical methods have made great progress in the qualitative examination of urine. Many reagents can now measure multiple items simultaneously. For example, urine protein, urine sugar, occult blood, bilirubin, urobilinogen, ketone bodies, specific gravity, nitrite, bacteriuria, etc. In addition to urinalysis, dry chemistry techniques can also be used to test samples such as whole blood, serum, and plasma.
The Reflomat system for the determination of blood glucose was first introduced in 1974 by the German company Paulingmann. In the 1980s, a variety of dry automatic biochemical analyzers were used for medical tests.
Advantages of dry chemistry analyzers
1) Fast
Rapid reporting reduces the waiting time for patients. This facilitates early diagnosis and timely treatment by clinicians and improves the quality of care.
2) Accuracy
Dry chemistry analyzers mostly use the reference method of wet chemistry as the reference measurement method. The accuracy of the dry chemistry method is acceptable when analyzed from the methodological comparison and recovery test results.
3) Precision
The precision of the dry chemistry method is better than that of the wet chemistry method because of its simple operation steps.
The Seamaty fully automated dry chemistry analyzer requires only 100ul of sample and supports whole blood, plasma or serum. It is extremely easy of use which does not require dedicated staff and allows anyone could operate it.
